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The Veterinary Clinics of North America. Small Animal Practice
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This review updates knowledge on pantropic canine coronavirus (CCoV), an emerging dog pathogen. It covers virology, epidemiology, clinical signs, diagnosis, and prevention, including experimentally induced disease.

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Area of Science:

  • Veterinary Virology
  • Canine Infectious Diseases

Background:

  • Canine coronavirus (CCoV) is an emerging pathogen affecting dogs.
  • Pantropic CCoV causes systemic disease with significant clinical impact.

Purpose of the Study:

  • To provide a comprehensive review of current literature on pantropic canine coronavirus.
  • To update knowledge on virologic, epidemiologic, clinical, diagnostic, and prophylactic aspects of CCoV infections.
  • To describe pantropic CCoV-induced disease experimentally.

Main Methods:

  • Literature review of available scientific articles on pantropic CCoV.
  • Synthesis of information on CCoV virology, epidemiology, and clinical manifestations.
  • Analysis of diagnostic methods and prophylactic strategies for CCoV.
  • Review of experimental studies reproducing pantropic CCoV disease.

Main Results:

  • Pantropic CCoV exhibits diverse virologic and epidemiologic characteristics.
  • Clinical signs of pantropic CCoV infection vary, often presenting systemically.
  • Effective diagnostic tools and prophylactic measures are crucial for CCoV control.
  • Experimental models confirm the pathogenicity of pantropic CCoV.

Conclusions:

  • Pantropic canine coronavirus represents a significant and evolving threat to canine health.
  • A thorough understanding of CCoV is essential for effective disease management and prevention.
  • Continued research is needed to further elucidate CCoV pathogenesis and develop improved interventions.