Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hamartomas.

S Poomeechaiwong1, L E Golitz

  • 1University of Colorado School of Medicine, Denver General Hospital.

Advances in Dermatology
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Skin hamartomas are benign growths present from birth or developing later. Some hamartomas can indicate internal issues or predispose to tumors, with genetic links in certain cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Benign cylindroma causing transcalvarial invasion in a patient with familial cylindromatosis.

Clinical neuropathology·2009
Same author

Primary noncutaneous melanoma.

Clinics in laboratory medicine·2001
Same author

The specialty of the treating physician affects the likelihood of tumor-free resection margins for basal cell carcinoma: results from a multi-institutional retrospective study.

Journal of the American Academy of Dermatology·2001
Same author

Sialadenoma papilliferum of the palate: case report and literature review.

Journal of cutaneous pathology·1999
Same author

The golden anniversary of the Spitz nevus.

Archives of dermatology·1999
Same author

Comparison of in vivo and in vitro measures of beryllium sensitization.

Journal of occupational and environmental medicine·1997
Same journal

Uncommon benign infantile vascular tumors.

Advances in dermatology·2009
Same journal

Advances in hair diseases.

Advances in dermatology·2009
Same journal

Cutaneous mosaicism: a molecular and clinical review.

Advances in dermatology·2009
Same journal

Current concepts: dermatopathology of pigmentary alteration disorders in the Hispanic population.

Advances in dermatology·2009
Same journal

Recent advances in acne vulgaris research: insights and clinical implications.

Advances in dermatology·2009
Same journal

Update on the natural history and systemic treatment of psoriasis.

Advances in dermatology·2009
See all related articles

Area of Science:

  • Dermatology
  • Genetics
  • Pathology

Background:

  • Skin hamartomas are congenital or acquired tumor-like malformations.
  • They represent abnormal development of mature skin structures.
  • Hamartomas can manifest at birth, in childhood, or early adulthood.

Purpose of the Study:

  • To describe the characteristics of skin hamartomas.
  • To highlight their association with systemic abnormalities.
  • To discuss their genetic and potential neoplastic implications.

Main Methods:

  • Review of histological and clinical presentations of skin hamartomas.
  • Analysis of associated syndromes and genetic inheritance patterns.
  • Correlation of hamartomas with internal organ abnormalities and secondary tumor development.

Related Experiment Videos

Main Results:

  • Hamartomas exhibit diverse histological patterns involving single or multiple cell lines.
  • Certain hamartomas are markers for syndromes like epidermal nevus syndrome.
  • Some hamartomas, like organoid nevi, carry a risk of secondary tumor formation.
  • Genetic inheritance, including autosomal dominant traits, is observed in multiple lesions.
  • Tuberous sclerosis is linked to a specific chromosomal abnormality on chromosome 9.

Conclusions:

  • Skin hamartomas are complex malformations with varied clinical significance.
  • They can range from isolated lesions to indicators of systemic disease.
  • Understanding hamartoma subtypes is crucial for diagnosis, management, and genetic counseling.