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Related Concept Videos

Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Nocturnal asthma.

Harly Greenberg1, Rubin I Cohen

  • 1Division of Pulmonary, Critical Care and Sleep Medicine, The North Shore-LIJ Health System, Hofstra University School of Medicine, 410 Lakeville Road, New Hyde Park, NY 11042, USA.

Current Opinion in Pulmonary Medicine
|November 3, 2011
PubMed
Summary
This summary is machine-generated.

Nocturnal asthma exacerbations during sleep worsen asthma control and increase health risks. Chronotherapy and addressing comorbidities like sleep apnea may improve outcomes for this common, under-recognized condition.

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Published on: November 4, 2010

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Area of Science:

  • Pulmonology
  • Sleep Medicine
  • Circadian Biology

Background:

  • Sleep physiology and circadian rhythms can negatively impact asthma control.
  • Nocturnal asthma exacerbations represent a significant vulnerability during sleep.
  • This asthma phenotype is linked to poorer overall disease control and increased health risks.

Purpose of the Study:

  • To review the pathophysiological mechanisms of nocturnal asthma.
  • To explore current and emerging treatment strategies for nocturnal asthma.
  • To highlight the importance of recognizing and managing nocturnal asthma.

Main Methods:

  • Literature review of pathophysiological mechanisms.
  • Analysis of chronotherapeutic principles in asthma management.
  • Evaluation of comorbid conditions influencing nocturnal asthma.

Main Results:

  • Circadian variations and sleep physiology can adversely affect asthma control.
  • Chronotherapy, including timed administration of medications like long-acting bronchodilators and inhaled corticosteroids, may improve outcomes.
  • Obstructive sleep apnea prevalence is higher in severe asthma patients, suggesting a disease link.
  • The role of acid reflux and beta-2 adrenergic receptor polymorphisms in nocturnal asthma remains debated.

Conclusions:

  • Sleep poses a vulnerability for respiratory compromise in asthma patients.
  • Nocturnal asthma is associated with reduced sleep quality, daytime somnolence, and increased mortality.
  • Effective management of nocturnal asthma requires consideration of chronobiology and comorbid conditions.