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Eu(II)-containing cryptates as contrast agents for ultra-high field strength magnetic resonance imaging
Joel Garcia1, Jaladhar Neelavalli, E Mark Haacke
1Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, USA.
Abstract:
The relaxivity (contrast-enhancing ability) of Eu(II)-containing cryptates was found to be better than a clinically approved Gd(III)-based agent at 7 T. These cryptates are among a few examples of paramagnetic substances that show an increase in longitudinal relaxivity, r(1), at ultra-high field strength relative to lower field strengths.
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