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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: May 27, 2026

An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation
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[Deep brain stimulation in schizophrenia].

J Kuhn1, M Bodatsch, V Sturm

  • 1Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum der Universität Köln, Köln. jens.kuhn@uk-koeln.de

Fortschritte Der Neurologie-Psychiatrie
|November 4, 2011
PubMed
Summary
This summary is machine-generated.

Deep brain stimulation (DBS) shows promise for treating therapy-resistant schizophrenia symptoms. However, a complete understanding of DBS mechanisms and its impact on schizophrenia is needed before widespread clinical use.

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Last Updated: May 27, 2026

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Published on: May 19, 2016

Area of Science:

  • Neuroscience
  • Psychiatry

Context:

  • Deep brain stimulation (DBS) is an established therapy for certain treatment-resistant neuropsychiatric disorders.
  • Schizophrenia, characterized by severe and intractable symptoms, is increasingly considered a potential indication for DBS.

Purpose:

  • To critically evaluate the mechanisms of DBS and its potential influence on schizophrenia pathophysiology.
  • To assess the feasibility and transferability of DBS from other psychiatric disorders to schizophrenia.

Summary:

  • The study reviews current DBS approaches and theories, considering animal models, effects on dopaminergic transmission, neural oscillations, and synchronization in schizophrenia.
  • It synthesizes existing knowledge to evaluate DBS's potential for schizophrenia treatment.

Impact:

  • DBS presents a promising avenue for managing specific schizophrenia symptoms.
  • Further research into comprehensive theories of DBS mechanisms and its precise impact on schizophrenia is crucial for its clinical application.