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Expression of Exogenous Cytokine in Patient-derived Xenografts via Injection with a Cytokine-transduced Stromal Cell Line
Published on: May 10, 2017
Strontium promotes cell proliferation and suppresses IL-6 expression in human PDL cells
Piero Römer1, Benjamin Desaga, Peter Proff
1University Medical Center Regensburg, Department of Orthodontics, Germany. piero.roemer@gmx.de
Abstract:
This study was designed to investigate the effect of strontium on human PDL cells in vitro. Strontium is used to treat osteoporosis because of its bone formation promoting effect on osteoblast cells. This investigation presents evidence that strontium promotes PDL cell proliferation. Simultaneously, strontium suppresses the expression of the inflammation-promoting cytokine IL-6. The observed effect of strontium on PDL cells supports its use it in guided dental tissue regeneration.
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