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Updated: May 27, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
Published on: May 23, 2025
Surgical and technical aspects of hand transplantation: is it just another replant?
Tristan L Hartzell1, Prosper Benhaim, Joseph E Imbriglia
1Division of Plastic Surgery, Department of Orthopedic Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095, USA. tristanhartzell@gmail.com
Abstract:
The ultimate goal of hand allotransplantation is to achieve graft survival and useful long-term function. To achieve these goals, selection of the appropriate patient, detailed preoperative planning, and precise surgical technique are of paramount importance. Transplantation should be reserved for motivated consenting adults in good general heath, who are psychologically stable and have failed a trial of prosthetic use. While the key surgical steps of transplantation are similar to those of replantation, there are major differences. This article describes the steps in hand allotransplantation, and the importance of patient selection as well as preoperative and postoperative care.
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