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Updated: May 27, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[Silent celiac disease among 21 patients with cryptogenic epilepsy]
Ana María Madrid S1, Mario Díaz S, Carmen Hurtado H
1Laboratorio Gastroenterología, Sección de Gastroenterología, Departamento de Medicina Interna, Hospital Clínico Universidad de Chile, Chile. anamariamadrid@gmail.com
Background:
Celiac disease (CD) is predominant in women and young people. Atypical, non-enteric symptoms are more common among adults. There is also an association between CD and neurological disorders, especially with cerebellar ataxia, polyneuropathy and epilepsy.
Aim:
To study the frequency of CD in a group of adults with cryptogenic epilepsy.
Material And Methods:
Twenty one patients with cryptogenic epilepsy, aged 20 to 65 years (14 women) were studied, measuring IgA-anti transglutaminase antibodies and deamidated gliadin peptide (DGP) IgG and IgA antibodies.
Results:
One patient had elevated titers of both types of antibodies. Small bowel biopsy showed villous atrophy and lymphocytic infiltration compatible with CD.
Conclusions:
One of 21 adult patients with cryptogenic epilepsy had a silent CD.
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