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Hypertension in adult after operation of aortic coarctation

G Palma1, R Giordano, V Russolillo

  • 1Department of Clinical Medicine and Cardiovascular Sciences, University of Naples Federico II, Naples, Italy.

The Journal of Cardiovascular Surgery
|November 5, 2011
PubMed

Insights

Surgical repair of coarctation of the aorta effectively resolves systolic hypertension in adults, significantly reducing the need for blood pressure medication post-operation.

Area of Science:

  • Cardiovascular Surgery
  • Adult Congenital Heart Disease
  • Hypertension Management

Background:

  • Coarctation of the aorta repair benefits in adults with systolic hypertension are debated.
  • Adult patients with critical systolic hypertension underwent coarctation repair.

Purpose of the Study:

  • To evaluate the effectiveness of coarctation repair in resolving adult systolic hypertension.
  • To assess the impact of surgical intervention on antihypertensive medication requirements.

Main Methods:

  • 65 adult patients (≥16 years) with critical systolic hypertension (SBP ≥140 mmHg) underwent coarctation repair.
  • Mean preoperative SBP was 163.5 ± 17.6 mmHg; 74% were on antihypertensive medication.
  • Follow-up ranged from 2 to 144 months (mean 68 months).

Main Results:

  • 87% of patients (53/61) with preoperative hypertension became normotensive (SBP <140 mmHg) post-repair.
  • Mean postoperative SBP decreased to 122.5 ± 12.4 mmHg.
  • 67% of patients (41/61) were medication-free at follow-up.

Conclusions:

  • Surgical repair of aortic coarctation in adults effectively resolves systolic hypertension.
  • Coarctation repair significantly reduces the need for antihypertensive medication in adult patients.
Abstract

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