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Cortical parcellations of the macaque monkey analyzed on surface-based atlases
David C Van Essen1, Matthew F Glasser, Donna L Dierker
1Department of Anatomy & Neurobiology, Washington University School of Medicine, St. Louis, MO 63110, USA. vanessen@wustl.edu
Surface-based registration aligns brain atlases for comparing macaque cortical areas. This study estimates 130-140 areas per hemisphere, aiding functional organization analysis.
Area of Science:
- Neuroscience
- Comparative Anatomy
Background:
- Surface-based atlases are crucial for analyzing cerebral cortex functional organization.
- Surface-based registration (SBR) is key for aligning individual brain hemispheres to atlases.
Purpose of the Study:
- To register diverse parcellation schemes to the macaque F99 surface-based atlas using landmark-constrained SBR.
- To enable objective comparison of similarities and differences across macaque cortical parcellations.
Main Methods:
- Utilized landmark-constrained surface-based registration (SBR).
- Registered multiple published parcellation schemes to the macaque F99 surface-based atlas.
Main Results:
- Successfully registered various parcellation schemes to the macaque F99 atlas.
- Cortical areas in macaques exhibit a wide range of surface areas (over two orders of magnitude).
- Estimated 130-140 neocortical and transitional cortical areas per macaque hemisphere based on a composite parcellation.
Conclusions:
- Landmark-constrained SBR facilitates objective cross-parcellation comparisons.
- Provides an estimated number of cortical areas in the macaque, crucial for understanding brain organization.
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