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Related Experiment Video

Updated: May 27, 2026

Juxtacellular Monitoring and Localization of Single Neurons within Sub-cortical Brain Structures of Alert, Head-restrained Rats
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Intracellular recording in behaving animals.

Michael A Long1, Albert K Lee

  • 1Department of Otolaryngology, NYU School of Medicine, 522 First Ave., New York, NY 10016, USA. mlong@nyumc.org

Current Opinion in Neurobiology
|November 8, 2011
PubMed
Summary
This summary is machine-generated.

Intracellular recordings in behaving animals reveal how single neurons process information. Advances allow these detailed neural recordings during complex natural behaviors, linking cellular function to systems neuroscience.

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Area of Science:

  • Neuroscience
  • Cellular Neuroscience
  • Systems Neuroscience

Background:

  • Electrophysiological recordings offer insights into neuronal function.
  • Intracellular approaches reveal neuron inputs and intrinsic properties, crucial for spiking output.

Purpose of the Study:

  • To highlight the significance of intracellular recordings in behaving animals.
  • To demonstrate how technical advancements enable these recordings during diverse behaviors.

Main Methods:

  • Intracellular electrophysiological recordings.
  • Behavioral paradigms in head-fixed and freely moving animals.

Main Results:

  • Recordings provide unparalleled views into the functional role of individual neurons.
  • These methods yield fundamental insights into cellular and circuit mechanisms.
  • Direct links are forged between cellular and systems neuroscience.

Conclusions:

  • Intracellular recordings are vital for understanding neural activity during natural behaviors.
  • Technical progress expands the scope of these investigations.
  • This approach bridges cellular and systems levels of neuroscience.