Related Experiment Video
Updated: May 27, 2026
Valorization of the Red Seaweed Gracilaria gracilis Through a Biorefinery Approach
Published on: November 21, 2023
Biological activity and stability of mangosteen as a potential natural color
Nattaya Lourith1, Mayuree Kanlayavattanakul
1School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand. nattayal@mfu.ac.th
Abstract:
Mangosteen pericarp color indicates antioxidant activity relating to the concentration of phenolics and flavonoids. The extract moderately inhibited Bacilus subtilis and was found to be stable at a concentration of 1.0 mg/mL at pH 3 at 23 °C over 7 d. Mangosteen pericarp extracts can therefore be used in pharmaceutical products that require low to medium pH.
Insights
Mangosteen pericarp extracts show antioxidant activity and stability at low pH, indicating potential for pharmaceutical applications. These natural compounds offer benefits for products requiring specific acidity levels.
Area of Science:
- Pharmacognosy
- Natural Product Chemistry
- Microbiology
Background:
- Mangosteen pericarp is rich in phenolics and flavonoids, known for antioxidant properties.
- The color of mangosteen pericarp correlates with its antioxidant potential.
- Understanding the stability of plant extracts is crucial for pharmaceutical development.
Purpose of the Study:
- To investigate the antioxidant activity of mangosteen pericarp extracts.
- To assess the stability of these extracts under specific pH and temperature conditions.
- To determine the suitability of mangosteen pericarp extracts for pharmaceutical use.
Main Methods:
- Extraction of compounds from mangosteen pericarp.
- Assay of antioxidant activity.
- Microbiological inhibition testing against Bacillus subtilis.
- Stability testing at pH 3, 23 °C over 7 days.
Main Results:
- Mangosteen pericarp extracts exhibit antioxidant activity linked to phenolic and flavonoid content.
- The extract demonstrated moderate inhibition of Bacillus subtilis.
- Extract stability was confirmed at 1.0 mg/mL concentration, pH 3, and 23 °C for 7 days.
Conclusions:
- Mangosteen pericarp extracts possess significant antioxidant and moderate antimicrobial properties.
- The demonstrated stability at low pH makes mangosteen pericarp extracts viable for pharmaceutical formulations.
- These findings support the use of mangosteen pericarp in developing new pharmaceutical products.