α1,3 glucans are dispensable in Aspergillus fumigatus
Christine Henry1, Jean-Paul Latgé, Anne Beauvais
1Unité des Aspergillus, Institut Pasteur, Paris, France.
Eukaryotic Cell
|November 8, 2011
Abstract:
A triple α1,3 glucan synthase mutant of Aspergillus fumigatus obtained by successive deletions of the three α1,3 glucan synthase genes (AGS1, AGS2, and AGS3) has a cell wall devoid of α1,3 glucans. The lack of α1,3 glucans affects neither conidial germination nor mycelial vegetative growth and is compensated by an increase in β1,3 glucan and/or chitin content.


