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Updated: May 27, 2026
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Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
Heterotopic ossification after total ankle arthroplasty.
1Yonsei University College of Medicine, Department of Orthopaedic Surgery, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea.
The Journal of Bone and Joint Surgery. British Volume
|November 8, 2011
Summary
Heterotopic ossification after total ankle replacement did not correlate with clinical outcomes. This finding suggests caution when considering surgery for heterotopic bone in the posterior ankle.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
Background:
- Heterotopic ossification (HO) is a potential complication after orthopedic procedures.
- Its impact on clinical outcomes following total ankle replacement (TAR) requires further investigation.
Purpose of the Study:
- To evaluate the incidence of HO after TAR.
- To determine if the degree of HO correlates with clinical outcomes.
Main Methods:
- Prospective evaluation of 90 ankles in 81 patients undergoing TAR.
- Assessment of HO based on proportional joint involvement.
- Correlation analysis to link HO with clinical outcomes.
Main Results:
- No significant association was found between HO formation and clinical outcomes.
- HO in the posterior ankle did not correlate with posterior ankle pain (p=0.929).
- HO did not correlate with American Orthopaedic Foot and Ankle Society (AOFAS) scores (p=0.454) or range of motion (p=0.283).
Conclusions:
- Clinical symptoms and functional limitations after TAR should not be solely attributed to HO.
- Caution is advised when considering surgical excision of posterior ankle HO.
- Further research may explore other factors influencing outcomes after TAR.
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