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Related Experiment Video

Updated: May 27, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

Intraocular pressure changes following modified e.C.T.

G D Shukla¹, U C Sharma, A N Mehrotra

¹Lecturer in Psychiatry, M.L.B. Medical College, Jhansi (U.P.).

Indian Journal of Psychiatry

|November 8, 2011

Summary

This summary is machine-generated.

Modified electroconvulsive therapy (ECT) increases intraocular pressure. Succinylcholine exacerbates this rise, causing a more significant and prolonged elevation in eye pressure during the procedure.

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Last Updated: May 27, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

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Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

Area of Science:

Anesthesiology
Ophthalmology
Neurology

Background:

Electroconvulsive therapy (ECT) is a medical treatment.
Understanding its physiological effects, such as on intraocular pressure (IOP), is crucial for patient safety.
The role of muscle relaxants like succinylcholine in modifying these effects requires investigation.

Purpose of the Study:

To investigate and compare intraocular pressure changes during modified ECT.
To determine the specific impact of succinylcholine administration on IOP during modified ECT.

Main Methods:

A study was conducted involving sixty cases undergoing modified ECT.
Intraocular pressure was monitored in two groups: those receiving modified ECT with succinylcholine and those without.
Changes in IOP were recorded and analyzed.

Main Results:

Intraocular pressure increased in both groups undergoing modified ECT.
The rise in IOP was more pronounced and lasted longer in the group that received succinylcholine.
This indicates a significant effect of succinylcholine on IOP during ECT.

Conclusions:

Modified ECT is associated with an increase in intraocular pressure.
Succinylcholine administration during modified ECT leads to a more substantial and sustained elevation of IOP.
Anesthesiologists and clinicians should consider these findings when managing patients undergoing ECT, particularly those with pre-existing ocular conditions.