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Related Experiment Video

Updated: May 27, 2026

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

Organs-on-a-chip: a focus on compartmentalized microdevices.

Christopher Moraes1, Geeta Mehta, Sasha Cai Lesher-Perez

  • 1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

Annals of Biomedical Engineering
|November 9, 2011
PubMed
Summary

Microengineering creates artificial organ environments for studying diseases and biological processes. These advanced tissue-engineered platforms offer cost-effective, in vivo-like models for biomedical research.

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Area of Science:

  • Biomedical Engineering
  • Tissue Engineering
  • Microfluidics

Background:

  • Conventional techniques limit insights into complex in vivo biological systems.
  • In vivo studies are often costly and complex.
  • Microengineering offers novel approaches to simulate biological microenvironments.

Purpose of the Study:

  • To survey recent advancements in tissue-engineered platforms for simulating organ structure and function.
  • To discuss various approaches and technologies used in these microengineered systems.
  • To highlight microtechnologies that leverage compartmentalization for in vivo-like culture models.

Main Methods:

  • Review of recent literature on microengineered tissue platforms.
  • Focus on microtechnologies utilizing compartmentalization.

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Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
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Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Combining Human Organoids and Organ-on-a-Chip Technology to Model Intestinal Region-Specific Functionality
10:56

Combining Human Organoids and Organ-on-a-Chip Technology to Model Intestinal Region-Specific Functionality

Published on: May 5, 2022

Related Experiment Videos

Last Updated: May 27, 2026

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Combining Human Organoids and Organ-on-a-Chip Technology to Model Intestinal Region-Specific Functionality
10:56

Combining Human Organoids and Organ-on-a-Chip Technology to Model Intestinal Region-Specific Functionality

Published on: May 5, 2022

  • Analysis of systems designed to mimic in vivo organ microenvironments.

    • Main Results:

    • Tissue-engineered platforms are increasingly capable of simulating organ systems.
    • Microtechnologies exploiting compartmentalization create more accurate in vivo models.
    • These systems offer potential for studying pathophysiology, development, and homeostasis.

    Conclusions:

    • Microengineering and tissue-engineered platforms provide powerful tools for biomedical research.
    • Simulating in vivo organ microenvironments can reduce experimental costs and complexity.
    • Further development of these technologies promises deeper insights into organ function and disease.