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Updated: May 27, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Pneumococcal endocarditis with extremely rapid valve destruction in a splenectomized host
Tanyanan Tanawuttiwat1, Brian Poustinchian, Adam Treitman
1Department of Medicine, Advocate Christ Medical Center, 4440 W. 95th Street, Oak Lawn, IL 60453, USA. ttanawuttiwat@gmail.com
Abstract:
A 45-year-old patient presented with fever and pneumococcal bacteremia. Transthoracic echocardiography, performed on the second day of admission, was unremarkable; however, repeat imaging performed only 60 h later showed destruction of posterior mitral valve leaflet with severe mitral regurgitation, and large, newly developed vegetations appearing on the mitral valve and the left ventricular outflow tract (LVOT). The patient underwent successful mitral valve replacement, with debridement of the LVOT vegetation. The findings of the present case illustrate the highly aggressive nature of pneumococcal endocarditis that is uncommonly encountered in the current, penicillin, era.
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