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[Simulation study of antithrombotic active fraction of Naodesheng by support vector machine]
Shu-xian Li1, Chao Chen, Shu-mei Wang
1School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China. lishuxian631@163.com
Objective:
To screen the antithrombotic active fraction of Naodesheng.
Methods:
The collagen and adrenaline-induced thrombosis by tail intravenous injection in mice was used. Based on orthogonal design, the support vector machine model was established for pharmacodynamics prediction of TCM prescriptions.
Results:
The model established in this study could predict the drug actions of different combinations.
Conclusion:
The pharmacodynamic actions of several formulas are superior to that of the original formula and CD has the best effect.
