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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

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WormBase 2012: more genomes, more data, new website.

Karen Yook¹, Todd W Harris, Tamberlyn Bieri

¹Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA. kyook@wormbase.org

Nucleic Acids Research

|November 10, 2011

Summary

This summary is machine-generated.

WormBase has expanded to 15 species, enhancing data curation through automation and improved website accessibility. New features facilitate discovery and data mining for researchers in biomedical and agricultural fields.

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Area of Science:

Bioinformatics
Genomics
Model Organism Databases

Background:

WormBase has evolved since 2000 from a single-species resource to a comprehensive database covering 15 species.
It serves crucial roles in biomedical and agricultural research.

Purpose of the Study:

To report on the growth and development of the WormBase database.
To detail enhancements in data curation, accessibility, and user experience.
To introduce a redesigned WormBase website and its new features.

Main Methods:

Automated identification and extraction of data from scientific literature.
Collaboration with journals to link publications to WormBase entities.
Integration of large-scale datasets and development of new data visualization tools.
Overhaul of the WormBase website with a focus on usability and customization.
Implementation of a public RESTful API for data mining and extensions.

Main Results:

Expansion of WormBase to include 15 species.
Enhanced curation rates through automated data processing.
Improved data accessibility via journal collaborations and a new website interface.
New interactive and customizable website features, including species-agnostic views.
Availability of a RESTful API for custom data analysis.

Conclusions:

WormBase has significantly grown and improved its data management and accessibility.
The redesigned website and new API empower researchers with enhanced data discovery and mining capabilities.
Ongoing efforts ensure WormBase keeps pace with user demands and scientific advancements.