Translating evidence-based interventions into practice: the design and development of the Merck Childhood Asthma...

Area of Science:

• Public Health
• Pediatric Medicine
• Health Services Research

Background:

• Pediatric asthma is a complex, multifactorial disease requiring comprehensive interventions.
• Effective translation of evidence-based interventions into practice is crucial for managing childhood asthma.
• The Merck Childhood Asthma Network (MCAN) was established to bridge the gap between asthma research and real-world application.

Purpose of the Study:

• To identify efficacious pediatric asthma interventions in urban U.S. settings suitable for replication.
• To facilitate the translation of these interventions into wider practice.
• To promote service and system integration for pediatric asthma care.

Main Methods:

• Conducted an extensive literature review and stakeholder engagement.
• Evaluated funding gaps to inform program development.
• Selected program sites based on demonstrated intervention efficacy and capacity for integration.

Main Results:

• Identified a need for effective, replicable pediatric asthma interventions in urban settings.
• Selected mature institutions with existing infrastructure and funding for program implementation.
• Focused on communities with high asthma morbidity to integrate comprehensive care approaches.

Conclusions:

• MCAN's phased approach successfully identified key areas for pediatric asthma intervention translation.
• Integration of healthcare, schools, and community organizations is vital for comprehensive pediatric asthma management.
• Site selection prioritized established organizations capable of immediate impact in high-need communities.