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Updated: May 27, 2026
06:23
Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
[Current coagulation diagnostics in intensive care medicine].
1Gerinnungsambulanz Südheide, Tiergarten 2, 29362, Hohne, Germany. t.lang@gerinnungsambulanz-suedheide.de
Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|November 10, 2011
Summary
A standardized bleeding history questionnaire is crucial preoperatively. Thrombelastometry offers rapid, detailed coagulation insights intraoperatively, guiding goal-directed coagulopathy management and reducing costs.
Area of Science:
- Anesthesiology and Perioperative Medicine
- Hematology and Coagulation Science
Background:
- Preoperative assessment of bleeding risk is essential for patient safety.
- Standard coagulation tests like the Quick test and activated partial thromboplastin time (APTT) provide limited information.
- Coagulopathy management often requires more comprehensive data than traditional tests offer.
Purpose of the Study:
- To evaluate the utility of thrombelastometry in assessing coagulation.
- To compare thrombelastometry with traditional coagulation tests in the perioperative setting.
- To highlight the benefits of goal-directed coagulopathy management.
Main Methods:
- Utilized thrombelastometry for rapid, comprehensive coagulation assessment.
- Compared thrombelastometry data with Quick test and APTT results.
- Analyzed the impact of goal-directed management on transfusion requirements and patient outcomes.
Main Results:
- Thrombelastometry provides crucial information on clot firmness and stability, beyond Quick test and APTT.
- Standard preoperative bleeding questionnaires remain indispensable.
- Thrombelastometry enables effective, goal-directed management of intraoperative coagulopathy.
Conclusions:
- Thrombelastometry significantly enhances perioperative coagulation assessment and management.
- Goal-directed management using thrombelastometry reduces blood product transfusions.
- Implementing thrombelastometry can lead to shorter hospital stays and substantial cost savings.
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