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Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

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Related Experiment Videos

Stiff skin syndrome--case report.

Adriana Gutstein da Fonseca Amorim1, Marcia Kalil Aidé, Sandra Maria Barbosa Durães

  • 1Universidade Federal Fluminense, Niterói, RJ, Brasil. adrianadermatologista@gmail.com

Anais Brasileiros De Dermatologia
|November 10, 2011
PubMed
Summary
This summary is machine-generated.

Stiff skin syndrome, a rare disorder causing hard skin and joint immobility, has no cure. Early diagnosis and supportive therapies are crucial for managing this condition in affected children.

Related Experiment Videos

Area of Science:

  • Dermatology
  • Pediatrics
  • Rare Diseases

Background:

  • Stiff skin syndrome (SSS) is a rare, scleroderma-like disorder of unknown cause.
  • It presents with severe skin hardening, hypertrichosis, and joint mobility limitations.

Observation:

  • A case study details a two-year-old boy with progressive skin hardening since eight months old.
  • The child exhibited secondary restricted joint mobility, consistent with SSS.

Findings:

  • The case highlights the characteristic symptoms of Stiff skin syndrome in a pediatric patient.
  • No effective treatments are currently established for SSS.

Implications:

  • This case underscores the importance of recognizing SSS symptoms for early diagnosis.
  • Rehabilitative therapy and exercise are vital for maintaining quality of life in patients with SSS.