Related Experiment Video
Updated: May 27, 2026

Evaluating Leaf Responses to Microbial Secondary Metabolites Using A High-Throughput Format
Published on: December 5, 2025
Modes of action of microbially-produced phytotoxins
Stephen O Duke1, Franck E Dayan1
1United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, P. O. Box 8048, MS 38677, USA.
Abstract:
Some of the most potent phytotoxins are synthesized by microbes. A few of these share molecular target sites with some synthetic herbicides, but many microbial toxins have unique target sites with potential for exploitation by the herbicide industry. Compounds from both non-pathogenic and pathogenic microbes are discussed. Microbial phytotoxins with modes of action the same as those of commercial herbicides and those with novel modes of action of action are covered. Examples of the compounds discussed are tentoxin, AAL-toxin, auscaulitoxin aglycone, hydantocidin, thaxtomin, and tabtoxin.
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