Related Experiment Video
Updated: May 27, 2026
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Structuring and validating a cost-effectiveness model of primary asthma prevention amongst children
G Feljandro P Ramos1, Sandra Kuiper, Edward Dompeling
1Department of General Practice, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, the Netherlands. feljandro.ramos@gmail.com
BMC Medical Research Methodology
|November 11, 2011
Summary
Developing a structured model for primary childhood asthma prevention is crucial for cost-effectiveness. This validated decision-tree model guides stakeholders in choosing between prevention strategies.
Area of Science:
- Health economics
- Pediatric respiratory medicine
- Decision science
Background:
- Rising asthma prevalence and healthcare costs necessitate effective prevention strategies.
- Existing research lacks sufficient cost-effectiveness data for primary asthma prevention programs.
- Decision analytic modeling can synthesize data for evaluating prevention strategy cost-effectiveness.
Purpose of the Study:
- To describe a procedure for structuring and validating a model for primary childhood asthma prevention.
- To address the need for transparent and credible cost-effectiveness models in public health.
Main Methods:
- An expert panel convened for round-table discussions to structure the cost-effectiveness model.
- Structural validity was assessed using descriptive validation with experts and parallel validation against existing models.
- A decision-tree structure was developed comparing current care with screening and prevention strategies.
Main Results:
- A decision-tree model was successfully developed, comparing current care with multifaceted and unifaceted prevention approaches for childhood asthma.
- The model's structural validity was confirmed through expert consensus (descriptive validation) and comparison with other models (parallel validation).
- No similar models addressing this specific decision problem were identified in the literature.
Conclusions:
- Expert-driven, systematic model development enhances transparency and credibility for cost-effectiveness evaluations.
- Parallel validation offers a practical method for validating novel decision-analytic models.
- The described process provides a framework for developing and validating future health intervention models.
Related Concept Videos
01:20Asthma: Pathogenesis and Management
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
01:30Asthma-IV: Diagnostic and Management
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
01:26Asthma-II: Pathophysiology and Classification
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
01:30Asthma-IV: Nursing Management
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
01:28Asthma I: Introduction
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
01:29Asthma-I: Introduction
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...