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Towards improved asthma control in children by non-invasive home monitoring
Casper E W Gijsen1,2,3, Jan Lucas4, Jean W M Muris5,6
1CAPHRI - Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands. casper.gijsen@maastrichtuniversity.nl.
Insights
Digital home monitoring using smartwatches can help detect early signs of worsening asthma control in children. Increased nocturnal heart rate is a key indicator of deteriorating childhood asthma, suggesting potential for improved management.
Area of Science:
- Pediatric Pulmonology
- Digital Health
- Asthma Management
Background:
- Uncontrolled childhood asthma significantly impacts quality of life.
- Traditional follow-up visits may not capture all instances of poor asthma control.
- Effective symptom monitoring is crucial for managing pediatric asthma.
Purpose of the Study:
- To evaluate the effectiveness of digital home monitoring in detecting early signs of asthma deterioration in children.
- To assess if non-invasive vital parameter measurements, medical feedback, and coaching improve asthma control.
- To explore the relationship between digital monitoring data and asthma control metrics.
Main Methods:
- A 12-week prospective single-arm study involving 40 children (ages 6-18) with asthma.
- Home monitoring included an app, smartwatch for vital parameters, and spirometer for lung function.
- Collected continuous vital signs, monthly (Childhood) Asthma Control Test ((C)-ACT) scores, and weekly lung function data.
Main Results:
- Increased nocturnal heart rate was significantly associated with worsening (C)-ACT scores (OR: 2.11, p=0.032), independent of Salbutamol use.
- (C)-ACT scores showed a trend towards improvement (22.5 to 24, p=0.063), but lung function did not significantly change.
- Higher frequency of lung function testing correlated with worse (C)-ACT scores.
Conclusions:
- Non-invasive digital home monitoring shows promise for managing pediatric asthma.
- Nocturnal heart rate is a potential early indicator of asthma control deterioration in children.
- Further research is warranted to optimize digital monitoring strategies for pediatric asthma.
Abstract:
Uncontrolled asthma in children impairs quality of life, emphasizing the need for effective symptom monitoring. Traditional follow-up visits may miss episodes of poor asthma control. This study aimed to evaluate if digital home monitoring including non-invasive vital parameter measurements via a smartwatch, medical feedback, and coaching can detect early signs of disease deterioration and improve asthma control. In this twelve-week prospective single-arm intervention study, 40 children with asthma (ages 6-18) were monitored at home using an app, smartwatch, and spirometer. Continuous vital parameters, monthly (Childhood) Asthma Control Test ((C)-ACT) scores, and weekly home lung function measurements were collected. Medical feedback was provided based on specific cut-off values. Changes in asthma control were analyzed using multivariable logistic regression. An increase in nocturnal heart rate was significantly associated with worsening (C)-ACT scores (OR: 2.11, CI: 1.068-4.168, p = 0.032), even after adjusting for Salbutamol use. Although C-ACT scores showed a trend towards improvement (baseline: 22.5, study end: 24, p = 0.063), no significant change in lung function was observed. Additionally, a higher frequency of lung function testing was linked to worsening (C)-ACT scores. Increased nocturnal heart rate was significantly associated with deteriorating (C)-ACT scores. These findings suggest that non-invasive home monitoring has potential in managing paediatric asthma.
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