[T-lymphocyte diseases. Physiopathological and nosologic concepts (excluding cancer and graft rejection)]

The T-lymphocyte is at the heart of the physiopathological mechanism of most dysimmunity affections. Furthermore, some cases of granulomatosis, the immediate consequence of macrophagic disorder, come within the framework of T-lymphocyte diseases, épicritical centre of the complex process of cellular immunity. By reference to new knowledges about various actions of T-lymphocytes and their interactions with lymphocytes B and macrophages, and by reference to classic pathologic findings of diseases of immunity, the author's propose a new classification of these diseases, suggesting therapeutic reasearch in consideration of effect of drugs, especially immunostimulant treatments, on the immune system.