Related Experiment Video
Updated: May 27, 2026
05:12
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Family dysfunction differentially affects alcohol and methamphetamine dependence: a view from the Addiction Severity
Nagisa Sugaya1, Ayako Haraguchi, Yasukazu Ogai
1Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan. sugaya-ng@igakuken.or.jp
International Journal of Environmental Research and Public Health
|November 11, 2011
Summary
Family dysfunction differentially impacts alcohol and methamphetamine dependence. Poor family relationships correlate with psychiatric issues in alcohol dependence and relationship difficulties in methamphetamine dependence.
Area of Science:
- Psychiatry
- Addiction Medicine
- Sociology
Background:
- Family dysfunction is a significant factor in substance dependence.
- Understanding its differential impact on various substance use disorders is crucial for targeted interventions.
Purpose of the Study:
- To investigate the distinct effects of family dysfunction on alcohol dependence versus methamphetamine dependence in a Japanese male patient cohort.
- To identify specific family relationship issues associated with problem severity in different domains.
Main Methods:
- Utilized the Addiction Severity Index (ASI) through semi-structured interviews.
- Assessed 321 male patients with alcohol dependence and 68 male patients with methamphetamine dependence.
- Evaluated seven functional domains: Medical, Employment/Support, Alcohol use, Drug use, Legal, Family/Social relationships, and Psychiatric.
Main Results:
- Alcohol dependence: Poor relationships with parents, siblings, and friends linked to psychiatric problems; poor sibling/partner relationships linked to employment issues; poor partner relationships linked to family/social issues.
- Methamphetamine dependence: Difficulty forming relationships with fathers noted; psychiatric problems correlated with medical, employment/support, and family/social issues.
- Family relationships significantly associated with psychiatric problems in both groups.
Conclusions:
- Family dysfunction exerts differential influences on alcohol and methamphetamine dependence.
- Family relationships are strongly implicated in psychiatric comorbidities associated with substance dependence.
- The ASI is a valuable tool for assessing multifaceted problems in substance dependence.
More Related Videos
07:31Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
09:16A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
Published on: January 22, 2016
Related Concept Videos
01:17Drug Dependence
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
01:15Drug Abuse and Addiction: Pharmacological Phenomena
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
01:24Substance Use Disorders Affecting Sleep
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
01:30Stress and Mental Health
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
01:27CNS Depressants: Alcohol and Nicotine
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
01:30Attention-Deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.