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Ischemic Stroke ll: Pathophysiology

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

Ischemic Stroke l: Introduction

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

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Related Experiment Video

Updated: May 27, 2026

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

The Mauk Model for Poststroke Recovery: assessing the phases.

Kristen L Mauk¹, Constance Lemley, Julie Pierce

¹Valparaiso University, IN, USA. kris.mauk@valpo.edu

Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses

|November 12, 2011

Summary

Nursing students effectively used the Mauk Model to identify stroke recovery phases. This pilot study highlights the model

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A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats

A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats

Published on: November 6, 2019

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Last Updated: May 27, 2026

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats

A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats

Published on: November 6, 2019

Area of Science:

Nursing
Neurology
Healthcare Education

Background:

An estimated 795,000 strokes occur annually in America, necessitating effective nursing care models for survivors.
Existing practical models for guiding nurses in post-stroke recovery care are limited.
The Mauk Model for Poststroke Recovery offers a theoretical framework detailing six distinct phases of recovery.

Purpose of the Study:

To evaluate nursing students' application of the Mauk Model in identifying post-stroke recovery phases.
To assess the Mauk Model's utility as a practical tool for nursing students using patient case examples.

Main Methods:

A pilot study involved 30 volunteer nursing students.
Students analyzed five patient case studies to determine the corresponding stroke recovery phase using the Mauk Model.
Descriptive statistics were calculated for sample characteristics and frequency of correct phase identification.

Main Results:

Nearly 57% (n=17) of the nursing students accurately identified the stroke recovery phase for all five case studies.
This indicates a strong initial grasp of the Mauk Model's application by students.

Conclusions:

The Mauk Model demonstrates potential as a valuable tool for assessing stroke recovery phases in nursing education.
Further clarification and refinement of the model may enhance its practical application and effectiveness in clinical settings.