Related Experiment Video
Updated: May 27, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
Peri-appendiceal inflammation in an 8-year-old child with chronic ulcerative colitis
Reka Szigeti1, Milton J Finegold, Richard Kellermayer
1Department of Pathology, Baylor College of Medicine, Houston, Texas, U.S.A.
Insights
The peri-appendiceal red patch (PARP) is linked to ulcerative colitis (UC) but is poorly documented in pediatric literature. This study presents the youngest patient with PARP, offering insights into UC in children.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Pathology
Background:
- Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
- Non-pancolonic UC can present with specific appendiceal findings.
Observation:
- The peri-appendiceal red patch (PARP), also known as appendiceal orifice inflammation (AOI), is a recognized complication of UC.
- This manifestation is underrepresented in pediatric pathology and gastroenterology literature.
Findings:
- This report details the youngest patient diagnosed with PARP associated with UC.
- The case highlights the importance of recognizing PARP in pediatric UC evaluations.
Implications:
- Increased awareness of PARP in pediatric UC may improve diagnosis and management.
- Further research is needed to understand the prevalence and significance of PARP in pediatric inflammatory bowel disease.
Abstract:
The peri-appendiceal red patch (PARP) or appendiceal orifice inflammation (AOI) is a known complication of non-pancolonic ulcerative colitis (UC), but it is not well documented in the pediatric pathology and gastroenterology literature. Here we describe the youngest patient with this manifestation to date and provide a brief review on PARP associated UC.
More Related Videos
04:05A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
Published on: May 31, 2024
15:49Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Related Concept Videos
Appendicitis
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Ulcerative Colitis