Related Experiment Video
Updated: May 27, 2026

Tension-Free Weight-Bearing Model of Steroid-Induced Osteonecrosis of Femoral Head in Rats
Published on: September 27, 2024
Nonprescription steroids on the Internet
Christen L Clement1, Douglas B Marlowe, Nicholas S Patapis
1Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19106, USA. cmcdonald@tresearch.org
Many websites promote anabolic-androgenic steroids as safe and sell them without prescriptions, often providing misinformation and downplaying dangers. Accurate health information and resources for cessation are rarely available online.
Area of Science:
- Pharmacology
- Public Health
- Internet Studies
Background:
- Anabolic-androgenic steroids (AAS) are performance-enhancing drugs with significant health risks.
- The internet has become a prevalent channel for the sale and promotion of various substances, including AAS.
Purpose of the Study:
- To assess the online availability and marketing of AAS.
- To analyze the information provided on websites selling AAS regarding their safety and risks.
Main Methods:
- Searched popular websites for specific AAS product labels (e.g., Dianabol) between March and June 2006.
- Evaluated website content for claims about safety, prescription requirements, and health risk information.
Main Results:
- Approximately 50% of websites promoted "safe" AAS use.
- Around 33% offered AAS for sale without requiring a prescription.
- Websites frequently contained misinformation, minimized AAS dangers, and rarely provided accurate health risk data or cessation resources.
Conclusions:
- Online platforms often misrepresent AAS, posing risks to users.
- There is a critical need for improved online health information, education, and prevention strategies regarding AAS.
- Policy interventions may be necessary to address the unsafe online marketing of AAS.
Related Concept Videos
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Transducer Mechanism: Nuclear Receptors
About 48 different soluble family members of nuclear receptors are identified that can be divided into two main classes:
Drug Nomenclature
Adrenergic Agonists: Mixed-Action Agents
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
Drug Classes and Categories
Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacokinetics
Instead, they are transported by the blood to different tissues. Muscles with a greater blood supply (arteries) and blood flow receive more...

