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Updated: May 27, 2026

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
Fundus autofluorescence in serpiginouslike choroiditis.
Amod Gupta1, Reema Bansal, Vishali Gupta
1Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. eyepgi@sify.com
Fundus autofluorescence imaging reveals distinct changes in serpiginous-like choroiditis lesions as they heal. This technique effectively tracks disease activity and lesion evolution from acute to resolved stages.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Serpiginous-like choroiditis is an inflammatory condition affecting the choroid.
- Understanding its progression is crucial for effective management.
Observation:
- Fundus autofluorescence (FAF) imaging was used to study 29 patients with presumed tubercular serpiginous-like choroiditis.
- FAF patterns were analyzed during acute, subacute, and healed stages of the lesions.
- Comparison was made with color fundus photography and fluorescein angiography.
Findings:
- FAF patterns evolved significantly with lesion healing.
- Acute lesions showed ill-defined hyperautofluorescence.
- Healed lesions transitioned to predominantly hypoautofluorescence, with stippled patterns observed in intermediate stages.
Implications:
- Fundus autofluorescence is a valuable tool for assessing disease activity in serpiginous-like choroiditis.
- FAF provides a rapid method for monitoring lesion progression and healing.
- This imaging modality aids in the clinical management of this condition.
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