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Updated: May 27, 2026

Mouse Complete Stasis Model of Inferior Vena Cava Thrombosis
Published on: June 15, 2011
Natural history of venous thromboembolism
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Diego School of Medicine, 200 West Arbor Drive, San Diego, CA 92103-8378, USA. t1morris@ucsd.edu
Abstract:
Venous thromboembolism (VTE) originates in systemic venous thrombosis and has different etiological mechanisms and natural history from arterial thrombosis. VTE typically originates as deep venous thrombosis in a lower extremity, where it may give rise to acute symptoms “upstream” from the obstructed vein, result in pulmonary embolism, and/or cause chronic venous obstruction. Pulmonary embolism may result in acute respiratory symptoms, cardiovascular collapse and, uncommonly, may also cause chronic disease.
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