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Related Concept Videos

Oral Drug Delivery Systems: Continuous-Release Systems01:26

Oral Drug Delivery Systems: Continuous-Release Systems

Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...
Modified-Release Drug Delivery Systems: Rate-Programmed II01:19

Modified-Release Drug Delivery Systems: Rate-Programmed II

Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...
Modified-Release Drug Delivery Systems: Classification01:23

Modified-Release Drug Delivery Systems: Classification

Modified-release drug delivery systems improve drug efficacy and minimize side effects by controlling the rate and location of drug release. These systems fall into three categories: rate-programmed, stimuli-activated, and site-targeted.Rate-programmed systems release drugs at a predetermined rate, maintaining consistent therapeutic levels and reducing fluctuations that could lead to toxicity or subtherapeutic effects. These systems use polymeric matrices, reservoir-based designs, or osmotic...
Modified-Release Drug Delivery Systems: Rate-Programmed I01:22

Modified-Release Drug Delivery Systems: Rate-Programmed I

Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...
Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
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Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...

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Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults
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Implement the RFID position based system of automatic tablets packaging machine for patient safety.

Ching-Hsiang Chang1, Yeong-Lin Lai, Chih-Cheng Chen

  • 1Chang Jung Christiant University, Tainan, Taiwan, Republic of China. joe@mail.cjcu.edu.tw

Journal of Medical Systems
|November 16, 2011
PubMed
Summary

This study introduces a Radio Frequency Identification (RFID) position-based system to prevent medication errors in Automatic Tablet Packaging Machines (ATPMs). The system ensures correct cassette placement, enhancing patient safety in hospital pharmacies.

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Area of Science:

  • Hospital Pharmacy Management
  • Patient Safety Systems
  • Medical Device Technology

Background:

  • Patient safety is paramount in hospital management, with medication dispensing being critical for accreditation.
  • Current Automatic Tablet Packaging Machines (ATPMs) lack error detection during cassette replenishment, increasing risks of human error.
  • Incorrect cassette placement can lead to significant adverse events for inpatients.

Purpose of the Study:

  • To design and implement a Radio Frequency Identification (RFID) position-based system (PBS) for ATPMs.
  • To enhance accuracy and prevent medication errors during cassette replenishment in hospital pharmacies.
  • To improve overall patient safety by addressing a critical gap in automated medication dispensing.

Main Methods:

  • Developed an RFID position-based system (PBS) utilizing passive high-frequency (HF) technology.
  • Attached HF tags to each cassette and installed HF readers on corresponding cabinet positions.
  • Implemented a system for verifying cassette ID numbers and positions, monitoring cassette orbits, and managing reader power for optimal drug storage temperature.

Main Results:

  • The RFID PBS successfully verifies the correct placement of cassettes within the ATPM.
  • The system provides real-time detection of misplaced cassettes, preventing potential errors.
  • Ensured appropriate environmental conditions for drug storage through controlled reader power consumption.

Conclusions:

  • The designed RFID PBS effectively prevents medication errors associated with cassette replenishment in ATPMs.
  • This system significantly contributes to enhancing patient safety in hospital pharmacy operations.
  • The RFID PBS offers a reliable solution for maintaining accuracy and safety in automated medication dispensing.