Related Experiment Video

Updated: May 27, 2026

Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter
07:53

Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter

Published on: June 16, 2022

[Study of traditional Chinese medicine pulse signals in patients with coronary heart disease based on recurrence

Rui Guo1, Yi-qin Wang, Jian-jun Yan

  • 1Laboratory of Information Access and Synthesis of Traditional Chinese Medicine Four Diagnosis, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine
|November 18, 2011
PubMed

Insights

Recurrence Quantification Analysis (RQA) of traditional Chinese medicine pulse signals reveals distinct nonlinear dynamics in coronary heart disease (CHD) patients. These RQA parameters offer a reliable method for differentiating CHD from normal subjects.

Area of Science:

  • Cardiovascular Medicine
  • Nonlinear Dynamics
  • Traditional Chinese Medicine (TCM)

Context:

  • Coronary heart disease (CHD) diagnosis remains a critical challenge in cardiovascular medicine.
  • Traditional Chinese Medicine pulse diagnosis offers a unique, non-invasive approach to health assessment.
  • Exploring nonlinear dynamics in physiological signals can reveal subtle disease-related patterns.

Purpose:

  • To apply Recurrence Quantification Analysis (RQA) to TCM pulse signals from CHD patients and healthy individuals.
  • To identify nonlinear dynamic parameters within pulse signals that can effectively distinguish between CHD and normal subjects.
  • To evaluate the diagnostic potential of these RQA parameters using receiver operating characteristic (ROC) curve analysis.

Summary:

  • Pulse signals were collected from 63 CHD patients and 61 normal subjects between October 2007 and June 2008.
  • RQA parameters, including recurrence rate (RR), determinism (DET), and trapping time (TT), showed significant differences between groups.
  • ROC curve analysis indicated high diagnostic value for RR, TT, Vmax, DET, and LAM, with areas under the curve ranging up to 1.000.

Impact:

  • Pulse signals from CHD patients exhibit greater certainty, regularity, and stability compared to normal subjects.
  • RQA provides a quantitative, data-driven method to interpret TCM pulse diagnosis for CHD.
  • This study highlights the potential of RQA as a non-invasive diagnostic tool for coronary heart disease.
Abstract

Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Special considerations while measuring pulse01:13

Special considerations while measuring pulse

Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Pulse amplitude and quality01:17

Pulse amplitude and quality

Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
Assessment of apical radial pulse01:25

Assessment of apical radial pulse

Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation