Related Experiment Video
Updated: May 27, 2026
![Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F2755.jpg&w=3840&q=50)
Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)
Published on: June 28, 2011
N-(2,6-Dichloro-phen-yl)succinamic acid.
This study details the crystal structure of C(10)H(9)Cl(2)NO(3), revealing specific molecular conformations and hydrogen bonding patterns. These findings contribute to understanding the solid-state arrangement of this dichloro-nitro compound.
Area of Science:
- Crystallography and Molecular Structure
- Organic Chemistry
- Solid-State Chemistry
Background:
- Understanding the three-dimensional arrangement of atoms within a crystal is crucial for predicting and explaining a compound's physical and chemical properties.
- Intermolecular forces, such as hydrogen bonds, play a significant role in dictating crystal packing and stability.
Purpose of the Study:
- To elucidate the precise crystal structure of the title compound, C(10)H(9)Cl(2)NO(3).
- To analyze the molecular conformation and identify intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the atomic arrangement and bond parameters.
- Conformational analysis was performed based on the determined crystal structure.
Main Results:
- The crystal structure of C(10)H(9)Cl(2)NO(3) was successfully determined.
- Specific anti conformations were observed for the amide O atom and the carbonyl O atom relative to adjacent groups.
- Molecules are organized into infinite chains via intermolecular O-H⋯O and N-H⋯O hydrogen bonds.
Conclusions:
- The study provides a detailed molecular and crystal structure of C(10)H(9)Cl(2)NO(3).
- The observed hydrogen bonding network highlights the importance of these interactions in the compound's solid-state organization.
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