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Updated: May 27, 2026
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Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
2,2-Dimethyl-5-(2,3,4-trimeth-oxy-benzyl-idene)-1,3-dioxane-4,6-dione.
1MicroScale Science Institute, Department of Chemistry and Chemical Engineering, Weifang University, Weifang 261061, People's Republic of China.
Acta Crystallographica. Section E, Structure Reports Online
|November 18, 2011
Summary
A novel compound, C(16)H(18)O(7), was synthesized. Its crystal structure reveals a distorted 1,3-dioxane ring stabilized by intermolecular hydrogen bonds, offering insights into molecular conformation and interactions.
Area of Science:
- Organic Chemistry
- Crystallography
- Chemical Synthesis
Background:
- Understanding the synthesis and structural properties of novel organic compounds is crucial in chemistry.
- 1,3-Dioxane derivatives are important scaffolds in organic synthesis.
- Elucidating crystal structures provides fundamental insights into molecular geometry and intermolecular forces.
Purpose of the Study:
- To synthesize and characterize a new organic compound with the molecular formula C(16)H(18)O(7).
- To investigate the conformational analysis of the 1,3-dioxane ring within the synthesized compound.
- To determine the intermolecular interactions stabilizing the crystal structure.
Main Methods:
- Chemical synthesis involving the reaction of 2,2-dimethyl-1,3-dioxane-4,6-dione and 2,3,4-trimethoxybenzaldehyde.
- Single-crystal X-ray diffraction for structural determination.
- Analysis of bond lengths, bond angles, and intermolecular interactions (hydrogen bonds).
Main Results:
- Successful synthesis of the target compound C(16)H(18)O(7).
- The 1,3-dioxane ring was observed to adopt a slightly distorted boat conformation.
- Weak intermolecular C-H⋯O hydrogen bonds were identified as the primary stabilizing forces in the crystal lattice.
Conclusions:
- The study successfully synthesized and structurally characterized a novel organic compound.
- The conformational flexibility of the 1,3-dioxane ring was demonstrated.
- The role of weak hydrogen bonding in crystal packing was highlighted, contributing to the understanding of supramolecular chemistry.
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