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Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
2-Cyano-N'-(5-hy-droxy-2-nitro-benzyl-idene)acetohydrazide monohydrate
1College of Chemistry and Biology Engineering, Yancheng Institute of Technology, Yancheng 224051, People's Republic of China.
Abstract:
The title compound, C(10)H(8)N(4)O(4)·H(2)O, was obtained by the reaction of 5-hy-droxy-2-nitro-benzaldehyde with cyano-acetohydrazide in methanol. The non-H atoms of the hydrazone molecule are approximately coplanar, with a mean deviation from the least-squares plane of 0.056 Å. In the crystal, mol-ecules are linked by N-H⋯O, O-H⋯N and O-H⋯O hydrogen bonds, generating a three-dimensional network.
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