Long-term adefovir plus lamivudine therapy does not decrease creatinine clearance in HBeAg-negative chronic hepatitis

Spilios Manolakopoulos1, Athanasia Striki, Melanie Deutsch

  • 12nd Academic Department of Internal Medicine, Hippokration Hospital of Athens, Athens, Greece. smanolak@med.uoa.gr

Summary

Long-term adefovir and lamivudine combination therapy did not independently cause significant renal dysfunction in patients with lamivudine-resistant hepatitis B. Age and baseline kidney function predict changes in renal function.

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