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Related Concept Videos

Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

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Related Experiment Video

Updated: May 27, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Postprostatectomy seizures: A case report.

Prasad Bichu1, Gautam Phadke, Harbaksh Sangha

  • 1Division of Nephrology, Department of Internal Medicine, University of Missouri, Columbia, Missouri 65212, USA. bichup@health.missouri.edu

Hemodialysis International. International Symposium on Home Hemodialysis
|November 19, 2011
PubMed
Summary

This case report highlights glycine toxicity following transurethral prostate surgery. Rapid dialysis reversed seizures and encephalopathy caused by toxic glycine metabolites, demonstrating the effectiveness of renal replacement therapy.

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Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser
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Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser

Published on: May 9, 2018

Related Experiment Videos

Last Updated: May 27, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser
07:17

Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser

Published on: May 9, 2018

Area of Science:

  • Nephrology
  • Toxicology
  • Urology

Background:

  • Transurethral resection of the prostate (TURP) is a common urological procedure.
  • Complications can arise from bladder irrigation solutions, such as glycine.
  • Glycine toxicity is a rare but potentially life-threatening condition.

Observation:

  • A 75-year-old male developed generalized seizures post-TURP due to intraperitoneal glycine extravasation.
  • Profound hyponatremia was noted, but serum osmolality was normal, suggesting glycine metabolites were osmotically active.
  • Encephalopathy and seizures were attributed to toxic glycine metabolites, particularly ammonia.

Findings:

  • The patient experienced seizures and encephalopathy linked to elevated ammonia and glycine levels.
  • Oligo-anuric renal failure developed postoperatively.
  • Slow low-efficiency dialysis for 8 hours effectively lowered ammonia and glycine levels, reversing neurological symptoms.

Implications:

  • This case underscores the risk of glycine toxicity after urological procedures involving glycine irrigation.
  • Early detection of glycine toxicity is crucial.
  • Renal replacement therapy, such as dialysis, plays a vital role in managing acute glycine toxicity and its neurological sequelae.