Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Obsessive-compulsive disorders in adolescents].

R G Klein1, J L Rapoport

  • 1New York State Psychiatric Institute, New York.

L'Encephale
|July 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hippocampal volume change relates to clinical outcome in childhood-onset schizophrenia.

Psychological medicine·2015
Same author

Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy.

Current molecular medicine·2015
Same author

Common polygenic variation and risk for childhood-onset schizophrenia.

Molecular psychiatry·2014
Same author

A Developmental Functional MRI Study of Prefrontal Activation during Performance of a Go-No-Go Task.

Journal of cognitive neuroscience·2013
Same author

High rate of disease-related copy number variations in childhood onset schizophrenia.

Molecular psychiatry·2013
Same author

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

Translational psychiatry·2012

Adolescent obsessive-compulsive disorder (OCD) shares clinical signs with adults but shows distinct neurological and neuropsychological differences. Early-onset OCD has more males, and clomipramine is effective, unlike other antidepressants.

Area of Science:

  • Child and Adolescent Psychiatry
  • Neuroscience
  • Psychology

Context:

  • Obsessive-compulsive disorder (OCD) in adolescents presents unique diagnostic and etiological considerations.
  • Understanding adolescent OCD is crucial due to its potential long-term impact on mental health.
  • Existing research often groups adolescent and adult OCD, potentially overlooking developmental differences.

Purpose:

  • To delineate the clinical, neurological, and neuropsychological characteristics of adolescent obsessive-compulsive disorder.
  • To compare adolescent OCD findings with those in adult populations.
  • To investigate the relationship between early onset, gender, comorbidities, and treatment response in adolescent OCD.

Summary:

  • Clinical presentation and comorbidities (anxiety, affective symptoms) in adolescent OCD are similar to adults.

Related Experiment Videos

  • Neurological and neuropsychological abnormalities are key distinguishing features in adolescent OCD.
  • Early-onset OCD is more prevalent in males; clomipramine shows efficacy, unlike other tricyclic antidepressants.

    • Impact:

    • Findings suggest adolescent OCD is not merely a variant of anxiety disorders, highlighting its distinct neurobiological underpinnings.
    • Identifies specific neurological markers that differentiate adolescent from adult OCD.
    • Informs targeted therapeutic strategies and diagnostic approaches for pediatric OCD populations.