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Accounting for artifactually elevated HbA2 in cases of Hb hope when measured by capillary electrophoresis

David F Keren, Lynn Rae Sample

    American Journal of Clinical Pathology
    |November 19, 2011
    PubMed
    Abstract

    No abstract available in PubMed .

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    Hemoglobin

    Hemoglobin is a globular protein made up of four subunits. Two of these subunits are alpha chains, and the other two are beta chains. Each subunit contains a molecule of heme, which has an iron atom and can bind to oxygen. When an oxygen molecule binds to one heme group, it changes the shape of hemoglobin, making it easier for the other heme groups to bind oxygen as well.
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