Related Experiment Video
Updated: May 27, 2026
09:37
An Integrated Approach for Microprotein Identification and Sequence Analysis
Published on: July 12, 2022
InterPro in 2011: new developments in the family and domain prediction database
Sarah Hunter1, Philip Jones, Alex Mitchell
1EMBL Outstation European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD Cambridge, UK. hunter@ebi.ac.uk
Nucleic Acids Research
|November 19, 2011
Summary
InterPro is a protein sequence analysis database. Recent updates enhance its protein family, domain, and functional site information, improving genome-wide and individual protein analysis.
Area of Science:
- Bioinformatics
- Computational Biology
- Protein Science
Background:
- InterPro integrates protein family, domain, and functional site data.
- It provides public access via web interfaces and services.
- Protein sequence searching against diagnostic models (signatures) determines function.
Purpose of the Study:
- To provide an overview of InterPro developments since 2009.
- To highlight updates in database content and curation.
- To describe enhancements to web and programmatic interfaces.
Main Methods:
- Database content updates.
- Refinement of curation processes.
- Improvements to web and programmatic interfaces.
Main Results:
- Expanded and updated protein family and domain information.
- Enhanced accuracy in protein function prediction.
- Improved accessibility and usability of InterPro resources.
Conclusions:
- InterPro continues to evolve as a key resource for protein sequence analysis.
- Recent developments enhance its utility for large-scale genomic and individual protein studies.
- The database remains a valuable tool for understanding protein function and evolution.
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