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Orthostatic hypotension among outpatients with ischemic stroke
Michael S Phipps1, Arlene A Schmid, John R Kapoor
1Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, CT, USA. michael.phipps@yale.edu
Journal of the Neurological Sciences
|November 22, 2011
Summary
Orthostatic hypotension affects about a quarter of stroke patients. Coronary artery disease is a risk factor, suggesting stroke patients need screening for this condition.
Area of Science:
- Neurology
- Cardiology
- Geriatrics
Background:
- Hypertension management is key for stroke prevention.
- Orthostatic hypotension complicates care for patients with cerebrovascular disease.
- Understanding orthostatic hypotension prevalence and risk factors in stroke patients is crucial.
Purpose of the Study:
- Determine the prevalence of orthostatic hypotension (OH) in a stroke outpatient clinic.
- Categorize the types of OH observed.
- Identify factors independently associated with OH in stroke patients.
Main Methods:
- Included veterans with stroke from a multidisciplinary clinic.
- Defined OH by a significant drop in blood pressure (BP) or symptomatic BP changes.
- Utilized multivariable logistic regression to analyze OH associations.
Main Results:
- 16 out of 60 (27%) stroke patients had OH.
- Among those with OH, BP status varied (hypertensive, normotensive, hypotensive).
- A history of coronary artery disease was independently linked to OH presence.
Conclusions:
- Orthostatic hypotension is common in stroke outpatients (approx. 27%).
- Coronary artery disease is identified as a potential risk factor for OH.
- Screening stroke patients for OH is recommended due to its potential impact on clinical management.
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