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Published on: March 21, 2013

Orthostatic hypotension among outpatients with ischemic stroke

Michael S Phipps1, Arlene A Schmid, John R Kapoor

  • 1Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, CT, USA. michael.phipps@yale.edu

Journal of the Neurological Sciences
|November 22, 2011
PubMed

Insights

Orthostatic hypotension affects about a quarter of stroke patients. Coronary artery disease is a risk factor, suggesting stroke patients need screening for this condition.

Area of Science:

  • Neurology
  • Cardiology
  • Geriatrics

Background:

  • Hypertension management is key for stroke prevention.
  • Orthostatic hypotension complicates care for patients with cerebrovascular disease.
  • Understanding orthostatic hypotension prevalence and risk factors in stroke patients is crucial.

Purpose of the Study:

  • Determine the prevalence of orthostatic hypotension (OH) in a stroke outpatient clinic.
  • Categorize the types of OH observed.
  • Identify factors independently associated with OH in stroke patients.

Main Methods:

  • Included veterans with stroke from a multidisciplinary clinic.
  • Defined OH by a significant drop in blood pressure (BP) or symptomatic BP changes.
  • Utilized multivariable logistic regression to analyze OH associations.

Main Results:

  • 16 out of 60 (27%) stroke patients had OH.
  • Among those with OH, BP status varied (hypertensive, normotensive, hypotensive).
  • A history of coronary artery disease was independently linked to OH presence.

Conclusions:

  • Orthostatic hypotension is common in stroke outpatients (approx. 27%).
  • Coronary artery disease is identified as a potential risk factor for OH.
  • Screening stroke patients for OH is recommended due to its potential impact on clinical management.
Abstract

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