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Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

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Appraising osteoporosis care gaps.

Thomas P Olenginski¹, Jana L Antohe, Elaine Sunderlin

¹Department of Rheumatology, Geisinger Medical Center, MC 21-52, 100 North Academy Avenue, Danville, PA 17822, USA. tpolenginski@geisinger.edu

Rheumatology International

|November 22, 2011

Summary

Physicians initiated osteoporosis drug therapy for 74% of high-risk patients following dual-energy X-ray absorptiometry (DXA) scans. One year later, 57% remained adherent to treatment, with side effects being the primary reason for discontinuation.

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Published on: September 28, 2017

Area of Science:

Osteoporosis Management
Bone Densitometry
Clinical Practice Evaluation

Background:

Dual-energy X-ray absorptiometry (DXA) is crucial for diagnosing osteoporosis.
Physician response and patient adherence to DXA reports impact long-term bone health.
Understanding treatment patterns is essential for optimizing osteoporosis care.

Purpose of the Study:

To assess physician response to DXA reports within a mobile program.
To evaluate prescription drug therapy initiation and adherence at one year.
To identify factors influencing treatment discontinuation.

Main Methods:

Retrospective analysis of 1381 DXA scans performed between October 2004 and March 2005.
Identification of 366 high-risk, drug-naïve patients for treatment initiation assessment.
Evaluation of laboratory test ordering for 191 patients with Z-scores ≤ -1.0.
Determination of one-year treatment adherence.

Main Results:

74% of high-risk patients received prescription therapy within 90 days of DXA.
57% of patients remained adherent to drug therapy at one year.
Adverse drug side effects were the main reason for treatment discontinuation.
Physicians ordered laboratory tests in 50% of cases with low Z-scores.

Conclusions:

The Mobile DXA Program effectively initiated treatment in a majority of high-risk patients.
One-year treatment adherence was moderate, highlighting the need to address side effects.
Physician ordering of laboratory tests for low Z-scores indicates further diagnostic evaluation.