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[Colonic motility in the irritable bowel syndrome]
J Frexinos1, L Bueno, J Fioramonti
1Service de Nutrition et de Gastroentérologie, CHU de Rangueil, Toulouse.
Gastroenterologie Clinique Et Biologique
|January 1, 1990
Summary
Investigating colonic motor disorders in irritable bowel syndrome (IBS) reveals ambiguities. While specific basal motility disturbances and stress-induced changes remain unclear, some patterns link motor activity to IBS symptoms.
Area of Science:
- Gastroenterology
- Neurogastroenterology
- Physiology
Context:
- Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder.
- Colonic motor dysfunction is recognized as a key factor in IBS pathophysiology.
- Current understanding of IBS-related colonic motility disturbances remains incomplete.
Purpose:
- To address fundamental questions regarding basal colonic motility in IBS.
- To investigate the impact of stress on colonic motor disorders.
- To determine the relationship between clinical symptoms and colonic motor abnormalities in IBS.
Summary:
- Basal colonic motility disturbances in IBS are not definitively established.
- Stress-induced motor changes in IBS vary depending on measurement methods.
- Specific motor patterns observed include segmental hyperactivity in constipation and altered responses to meals in bloating and diarrhea.
Impact:
- Long-term colonic myoelectric activity recording may enhance understanding of IBS motor disorders.
- Myoelectric abnormalities are present in approximately two-thirds of patients with functional intestinal disorders.
- Further research is needed to elucidate the precise role of colonic disorders in IBS pathophysiology, considering factors like visceral hypersensitivity and psychological influences.