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Related Concept Videos

Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Evolution of Microbial Genome01:08

Evolution of Microbial Genome

Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.
Genetic Screens02:46

Genetic Screens

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Related Experiment Video

Updated: May 27, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

GenomeView: a next-generation genome browser.

Thomas Abeel1, Thomas Van Parys, Yvan Saeys

  • 1Department of Plant Systems Biology, VIB, Technologiepark 927, 9052 Gent, Belgium. thomas@abeel.be

Nucleic Acids Research
|November 22, 2011
PubMed
Summary
This summary is machine-generated.

GenomeView is a new open-source genome browser for visualizing and manipulating large genomics datasets. It handles billions of nucleotide sequences, enabling dynamic browsing and interactive analysis of aligned genomes and short reads.

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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

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Related Experiment Videos

Last Updated: May 27, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • Sequencing technologies generate billions of nucleotide sequences daily.
  • Visualizing and analyzing large-scale genomics data presents a significant challenge for researchers.
  • Effective tools are needed for downstream analysis of high-volume sequence data.

Purpose of the Study:

  • To introduce GenomeView, a novel stand-alone genome browser.
  • To provide a tool for visualizing and manipulating diverse genomics data.
  • To enable interactive handling of large datasets including aligned genomes and short reads.

Main Methods:

  • Development of a stand-alone genome browser software package.
  • Implementation of dynamic navigation and semantic zooming for data exploration.
  • Design for interactive viewing and editing of genomics data.

Main Results:

  • GenomeView allows dynamic browsing of high-volume aligned short-read data from whole genome to single nucleotide levels.
  • The tool visualizes whole genome alignments of dozens of genomes against a reference sequence.
  • GenomeView interactively handles large datasets with thousands of annotation features and millions of mapped short reads.

Conclusions:

  • GenomeView offers a unique solution for visualizing and manipulating extensive genomics datasets.
  • The software facilitates interactive analysis of complex genomic information.
  • GenomeView is freely available as an open-source package, promoting accessibility in genomics research.