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Hyaluronic acid immobilization on the poly-allylamine coated nano-network TiO2 surface
Jae-Won Shim1, Kang Lee, Moon-Jin Jeong
1Department of Dental Materials, School of Dentistry, Chosun University, Gwangju, 501-759, Korea.
Abstract:
Recently, biocompatibility report revealed that the TiO2 nano-network (TiO2 NT) structure has much higher cells colonization than the native TiO2 on Ti surface. In this study, we prepared the hyaluronic acid (HA) immobilized TiO2 NT layer by plasma surface modification and then evaluated biological behavior of MC3T3-E1 on the Ti, TiO2 NT and TiO2 NT/NH2/HA surface. The cell viability tests revealed slightly enhanced viability on the TiO2 NT/NH2/HA surfaces than on the untreated Ti surfaces.
