Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Proteomic characterization of SMARCA-deficient esophageal adenocarcinoma reveals complement evasion and DNA repair-associated prognostic subgroups.

British journal of cancer·2026
Same author

MET Expression in Upper Gastrointestinal Adenocarcinoma: Prevalence, Prognostic Impact, and Implications for Anti-MET Antibody-Drug Conjugate Therapy.

International journal of cancer·2026
Same author

Deduction of Back Pain Patients Using EMG Technology and Inertial Sensors During Functional Tests.

Sensors (Basel, Switzerland)·2026
Same author

Adherens junction protein expression is associated with poor response to neoadjuvant FLOT chemotherapy and pro-inflammatory tumor microenvironment in esophageal adenocarcinoma.

International journal of cancer·2026
Same author

Cervical spine chordomas: surgical outcome assessment in a multicenter cohort from the Primary Tumor Research and Outcomes Network.

Journal of neurosurgery. Spine·2026
Same author

Insights From the AO Spine Knowledge Forum Tumor Registries: Advancing the Understanding and Management of Primary Spine Tumors Through International Multicentric Collaboration. A Narrative Review.

Global spine journal·2026

Related Experiment Video

Updated: May 27, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Pedicle-screw-based dynamic implants may increase posterior intervertebral disc bulging during flexion.

Hadi N Boustani1, Thomas Zander, Alexander C Disch

  • 1Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Germany.

Biomedizinische Technik. Biomedical Engineering
|November 23, 2011
PubMed
Summary

A dynamic implant reduced posterior disc bulging during extension, lateral bending, and rotation but increased it during flexion. Implant stiffness influenced the center of rotation, impacting disc compression.

More Related Videos

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
07:06

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

Published on: October 10, 2025

Related Experiment Videos

Last Updated: May 27, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
07:06

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

Published on: October 10, 2025

Area of Science:

  • Spine biomechanics
  • Orthopedic implant technology

Background:

  • Posterior disc bulging can cause nerve root compression, radicular pain, and back pain.
  • Disc bulging behavior differs between flexion and extension in an uninstrumented spine.

Purpose of the Study:

  • To evaluate the impact of a pedicle-screw-based dynamic implant on posterior disc bulging.
  • To analyze how implant stiffness and segment distraction affect disc bulging and center of rotation.

Main Methods:

  • Utilized a finite element model of the lumbosacral spine.
  • Simulated posterior disc bulging before and after dynamic implant placement under various loading conditions.
  • Varied implant stiffness and assessed segment distraction effects on disc bulging and center of rotation (CoR).

Main Results:

  • Dynamic implant use decreased posterior disc bulging during extension, lateral bending, and axial rotation compared to a non-instrumented spine.
  • Posterior disc bulging increased during flexion with the dynamic implant.
  • Increased implant stiffness shifted the CoR posteriorly, compressing the intervertebral disc during flexion and exacerbating disc bulging.

Conclusions:

  • Pedicle-screw-based dynamic implants can alter posterior disc bulging dynamics.
  • Implant-induced changes in the center of rotation are critical in understanding flexion-induced disc bulging.
  • Further research is needed to optimize dynamic implant design for managing disc bulging.