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Localised Mycobacterium ulcerans infection in four dogs
C R O'Brien1, E McMillan, O Harris
1University of Melbourne, Faculty of Veterinary Science, Parkville, Victoria, Australia. cob@catvet.net.au
Australian Veterinary Journal
|November 23, 2011
Summary
Mycobacterium ulcerans infection, a cause of skin ulcers in dogs, was identified in Victoria, Australia. Early diagnosis and treatment are crucial for successful outcomes in endemic areas.
Area of Science:
- Veterinary Dermatology
- Infectious Diseases
- Molecular Diagnostics
Background:
- Mycobacterium ulcerans causes localised infections, including the skin disease known as Buruli ulcer in humans.
- Canine infections with M. ulcerans are rare, with limited information on diagnosis and treatment.
Observation:
- Four dogs (two Kelpies, one Whippet, one Koolie) in Victoria, Australia, presented with localised skin lesions.
- Ulcerated lesions were sampled for diagnostic testing.
Findings:
- Real-time polymerase chain reaction (PCR) confirmed M. ulcerans infection in all four dogs.
- Molecular typing indicated that the M. ulcerans strain in three dogs was indistinguishable from strains found in humans and animals in Victoria.
- Environmental samples from dog homes showed low levels of M. ulcerans DNA.
Implications:
- Mycobacterium ulcerans infection should be considered in the differential diagnosis of canine skin ulcers in endemic regions of Australia.
- This study highlights the potential for M. ulcerans transmission to dogs and the importance of One Health approaches.
- Successful treatment outcomes were achieved with medical therapy and/or surgical debridement.
